visual
visual

세미나

  • HOME
  • >
  • 소식
  • >
  • 세미나
날짜 2024-01-24 15:00 
연사  
장소 E6-2 #1323 
물리학과 구성원분들께,
 
아래와 같이 세미나를 개최하오니, 관심있는 분들의 많은 참석 부탁드립니다.
 
* Title: Determination of single molecule loading rate during mechanotransduction
 
* Speaker: Myung Hyun Jo  (Boston Children's Hospital, Harvard Medical School)  조명현 박사
 
* Date: 3pm, 24th January 2024 (Wednesday)
 
* Place: E6 1323 (no zoom broadcasting)
 
Abstract:
Cells connect with their environment via surface receptors and utilize physical tension in receptor-ligand bonds for various cellular processes. Single-molecule techniques have revealed bond strength by measuring 'rupture force' but it has been long recognized that rupture force is dependent on the loading rate – how quickly force is ramped up. Therefore, the physiological loading rate must be determined to reveal the mechanical strength of individual bonds in their functional context. Here, we developed an overstretching tension sensor (OTS) allowing for more accurate force measurement in physiological conditions with single-molecular detection sensitivity even in mechanically dense and dynamic focal adhesions. Serially connected OTSs show that the physiological loading rate ranges from 0.5–4 pN/s and is about three times higher in leukocytes than in epithelial cells. 
 
Contact: Yongsoo Yang (yongsoo.yang@kaist.ac.kr)
번호 날짜 연사 제목
공지 2025-02-24 16:00    2025년 봄학기 콜로키움 안내
공지 2025-02-27 16:00    2025년 봄 물리학과 특별세미나 (광학/응집물리 분야)
365 2023-06-08 16:00    Thermal decoupling in high-Tc cuprate superconductors
364 2019-05-31 11:00    Cavity QED with Spin Qubits file
363 2022-05-27 11:00    Current Status and Future Plans of ADMX file
362 2015-07-23 13:30    Enhanced ZnO based UV photonics and related applications file
361 2020-10-15 16:00    Graphene-based Josephson junction microwave bolometer file
360 2022-06-03 11:00    (응집물리 세미나) Theoretical Investigation of Exotic Quantum States in Low-dimensional Materials
359 2025-06-26 16:00  Prof. Eun-Ah Kim (Cornell)  Attention to Quantum Complexity file
358 2023-03-27 15:00    A coherent mechanical oscillator pumped by a suspended quantum dot file
357 2022-09-21 16:00    Materials and Device Nanofabrication of Optical Metasurfaces file
356 2023-11-01 16:00    [High Energy Theory Seminar] Modular functions and 3D N=4 rank-zero superconformal field theories
355 2019-02-21 16:00    B-meson charged current anomalies - Theoretical status file
354 2023-03-30 16:00    Detecting axions with chiral magnetic effects file
353 2019-09-18 16:00    Fall 2019: Physics Seminar Serises file
352 2016-03-07 16:00    Physics Colloquium : 2016 Spring file
351 2023-11-15 16:00    Quantum hydrodynamic theory for plasmonics: from molecule-coupling to nonlinear optics
350 2022-10-04 16:00    Distinguishing 6d (1, 0) SCFTs
349 2015-03-04 12:00    Bioimaging and Biosensing Using Near-Infrared Fluorescence file
348 2019-05-03 11:00    Exotic Magnetism file
347 2014-12-22 14:00    Dynamics of molecular motors: Power stroke vs Brownian ratchet file
346 2019-05-30 16:00    Tuning the excitonic properties of semiconductors with light-matter interactions file