• HOME
  • >
  • 소식
  • >
  • 세미나
장소 KI bldg. 5th fl. Room B501 & Zoom 
일시 Jan. 18(Tue), 2pm-3pm 
연사 YoungJu Jo (Stanford University) 


18 Jan 2022, Tue, 2pm-3pm, KI bldg. 5th fl. Room B501


회의 ID: 895 860 324 30


Data-driven interrogation of biological dynamics:
from subcellular interactions to neuronal networks in vivo



YoungJu Jo

PhD Candidate in Applied Physics, Deisseroth Laboratory, Stanford University



Biological systems are nonlinear dynamical systems consisting of heterogeneous entities. Understanding the logic of the complex spatiotemporal dynamics in such systems, robustly implementing specific biological functions, may require new approaches beyond the traditional hypothesis-driven experimental designs. Here we present a data-driven approach, enabled by high-throughput experimental and computational technologies, across multiple scales. We first discuss a computational imaging technique for simultaneously visualizing multiple aspects of subcellular dynamics [1, 2], its potential combination with molecular optogenetics to study the cell signaling networks, and the remaining challenges in these systems. Then we turn to neuronal networks in behaving animals where high-dimensional neural population activity could be reliably measured and perturbed over extended time. Synergizing with recent technical advances, we propose and experimentally demonstrate a unified deep learning framework to identify the underlying neural dynamical systems, reverse-engineer the neural computation implemented by the dynamics, and design spatiotemporally patterned optogenetic stimulation for naturalistic manipulation of animal behavior [3]. Application of this framework to the mouse habenular circuitry reveals cell-type-specific reward history coding implemented by line attractor dynamics [4].



1. Jo*, Park* et al. Science Advances 3(8), e1700606, 2017.

2. Jo*, Cho*, Park* et al. Nature Cell Biology 23, 1329–1337, 2021.

3. Jo et al. in preparation.

4. Sylwestrak*, Vesuna*, Jo* et al. in revision.


문의: 박용근 교수 (내선:2514)



번호 일시 장소 연사 제목
338 Jun 8 (Tue), 10:00 AM  Zoom webinar  Toshihiko Baba (Yokohama National University, Japan)  Photonic crystal devices for sensing file
337 Sep. 14(Mon) 17:30~  Zoom webinar  Teruo Ono (Kyoto U. Japan)  KAIST Global Forum for Spin and Beyond (Third Forum) file
336 July 8(Mon), 14:00  E6, #1322  T. L. M. Guedes (Univ. of Konstanz)  Ultrabroadband squeezed pulses and their relation to relativity file
335 June 23th (Thur), 11:00  E6 Room(#1322)  Sun Yool Park(Joint Institute for Laboratory Astrophysics (JILA) & University of Colorado)  JILA’s search for the electron’s Electric Dipole Moment (eEDM) to probe physics beyond the standard model file
334 Jan. 11th(Tue), 15:00  E6 #1501  Soyeun Kim(UIUC)  Ultrafast optical studies on CDW collective modes of the Weyl-CDW (TaSe4)2I file
333 February 20 (Thu), 4:00 PM  #1323, E6-2  Seunghyun Khim  Unconventional superconductivity in the locally non-centrosymmetric heavy-fermion CeRh2As2 file
332 2016/09/29-12/13  E6-2, #1323  Sangyoon Han 외  2016 Fall, Physics Seminar Serises file
331 Nov. 2(Tue) 04:00pm  자연과학동(E6-2) #1323  Sangjin Lee(IBS-CALDES)  Metrology of Band Topology via Resonant Inelastic X-ray Scattering file
330 2015/07/16-07/17  E6-2, 1501  Sang-Wook Cheong (Rutgers Univ.)  KAIST Physics Distinguished Lecture
329 Nov. 28 (Tue.), 4:00 PM  #1323 (E6-2. 1st fl.)  Samindranath Mitra, Editor at Physical Review Letters  Physics after the lab and the desk: Your work in PRL file
328 April 15(Fri.) 11:00  Online seminar  Prof.Jaekwang Lee (Department of Physics, Pusan National University)  (응집물리 세미나) First-principles studies of polar oxides and their applications file
327 Apr. 27, 2017 (Thu) 4:00 pm  Seminar Room(#1323, E6-2)  Prof.Donghan Lee (Chungnam National Univ.)  반도체 양자점을 이용한 단광자 광원
326 September 18(Wed.), 16:00PM  #1323, E6-2  Prof.David Schuster  Exploring Synthetic Quantum Matter in Superconducting Circuits file
325 July 25(Thur.),4:00PM  E6-2, #1323  Prof.Bohm-Jung Yang  Band topology of twisted bilayer graphene file
324 2015/10/16, 4PM  E6-2. 2nd fl. #2501  Prof. Yung-Fu Chen(Solid-state Laser Physics Laboratory,National Central University)  Fluctuations of entropy production in partially masked electric circuits
323 Nov. 1 (Tue.) 2:30 pm  Seminar Room #1323(E6-2)  Prof. Youngjoon Kwon, Yonsei Univ.  Search for dark sector particles in the B-factory experiments
322 April 6, 2017 (Thu), 4:00 pm  IBS CAPP seminar room, Creation Hall (3F), KAIST Munji Campus  Prof. Youngjoon Kwon (Yonsei University)  For whom the Belle tolls
321 Dec.23(Wed), 10:00~16:00  Online  Prof. YongKeun Park (KAIST) and etc.  Online workshop for Quantitative Phase Imaging file
320 2015/10/23-12/4 10:30 AM  E6, #1501  Prof. YongKeun Park & Prof. Tae-Young Yoon  How to write a good scientific paper[Open lecture series]
319 May. 17 (Thu.), 01:30 PM  E6-2. 1st fl. #1323  Prof. Yong-Baek Kim University of Toronto  Quantum Spin Liquid in Kitaev Materials file