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장소 E4(KI Building), Connect room (2nd fl.) 
일시 2015/12/09, 11AM 
연사 Arjun G. Yodh (University of Pennsylvania) 

Functional Imaging & Monitoring of Brain & Breast with Diffuse Light


ABSTRACT
Functional diffuse optical imaging and spectroscopy of tissue is gaining momentum as a diagnostic in a variety of medical scenarios including breast cancer imaging, functional activation and clinical studies of brain, cancer therapy monitoring and the investigation of muscle disease [1, 2, 3]. After a short introduction to diffuse optics, I will review several recent clinical studies from my lab, particularly those oriented towards breast cancer and brain function. Central to the breast cancer effort is a pilot clinical trial [4] which has taken important steps towards quantitative assessment of diffuse optics for detection and characterization of tumors [5], and helps to spin-off problems such as cancer therapy monitoring. A second important application of diffuse optical methods is in the area of brain function and physiology wherein the interplay between tissue oxygen consumption, vascular supply, and regulatory effects remains poorly understood. The utility of this approach in brain will be demonstrated in several contexts, including the care of acute ischemic stroke (AIS) patients in the clinic [6, 7].


REFERENCES
1. Durduran, T., Choe, R., Baker, W.B, and Yodh, A.G., Reports on Progress in
Physics, 73, 076701 (2010).
2. Mesquita, R.C., Durduran, T., Yu, G., Buckley, E.M., Kim, M.N., Zhou, C., Choe, R., Sunar, U., Yodh, A.G., Philosophical Transactions of the Royal Society A 369, 4358-4379 (2011).
3. Durduran, T., and Yodh, A.G., Neuroimage 85, 51-63 (2014).
4. Choe, R., Konecky, S.D., Corlu, A., Lee, K., Durduran, T., Busch, D.R., Pathak, S., Czerniecki, B.J., Tchou, J., Fraker, D.L., DeMichele, A., Chance, B., Arridge, S.R., Schweiger, M., Culver, J.P., Schnall, M.D., Putt, M.E., Rosen, M.A., and Yodh, A.G., Journal of Biomedical Optics 14, 024020 (2009).
5. Busch, D.R., Choe, R., Rosen, M.A., Guo, W., Durduran, T., Feldman, M.D., Mies, C., Czerniecki, B.J., Tchou, J., DeMichele, A., Schnall, M.D., and Yodh, A.G., Biomedical Optics Express 4, 105-121 (2013).
6. Durduran, T., Zhou, C., Edlow, B.L., Yu, G., Choe, R., Kim, M.N., Cucchiara, B.L., Putt, M.E., Shah, Q., Kasner, S.E., Greenberg, J.H., Yodh, A.G., and Detre, J.A., Optics Express 17, 3884-3902 (2009).
7. Kim, M.N., Edlow, B.L., Durduran, T., Frangos, S., Mesquita, R.C., Levine, J.M., Greenberg, J.H., Yodh, A.G., and Detre, J.A., Nerocritical Care 20, 443-453, DOI
10.1007/s12028-013-9849-7 (2014).

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137 October 15 (Mon.), 16:00 PM  #1323, E6-2  Dr. Yongjoo Baek  Universal properties of macroscopic current-carrying systems file
136 April 11 (Wed), 1:30pm  #1323 (E6-2, 1st fl.)  Dr. Yongsoo Yang  Probing 3D Structure and Physical Properties of Materials at the Single-Atom Level file
135 May. 12 (Fri.), 01:30 PM  E6-2. 1st fl. #1323  Dr. Young Kuk Kim  Topological Dirac insulator
134 April 11 (Wed), 4:00pm  #1323 (E6-2, 1st fl.)  Dr. Young-Sik Ra  Non-Gaussian states of multimode light generated via hybrid quantum information processing file
133 May 13 (Fri.), 1:30 PM  E6. #1501(1st fl.)  Dr. Young-Woo Son, Dept. of Physics, KIAS  Aperiodic crystals in low dimensions
132 Mar. 16 (Fri.), 04:0 PM  E6-2. 1st fl. #1323  Dr. YoungDuck Kim  Van der Waals Heterostructures from Quantum Transport to Ultrafast Optoelectronics file
131 2015/11/06, 4:30 PM  E6-2, #5318  Dr. Youngkuk Kim (University of Pennsylvania)  Topological Dirac line nodes in centrosymmetric semimetals
130 Apr. 19 (Fri.), 02:30 PM  E6-2. 1st fl. #1323  Dr. YoungWoo Nam  A family of finite-temperature electronic phase transitions in graphene multilayers file
129 Nov. 1 (Fri.), 02:30 PM  E6-2. 1st fl. #1323  Dr. YoungWook Kim  Squeezing the best out of 2D materials file
128 Sep. 26 (Tue.), 11AM  #1323 (E6-2. 1st fl.)  Dr. Yukiaki Ishida / ISSP, University of Tokyo  Time-resolved ARPES study of Dirac and topological materials
127 Apr. 08 (Fri.), 13:30 PM  E6-2. 1st fl. #1501  Dr. Yunkyu Bang, Chonnam National Univ.  Theoretical Overview of Iron-based superconductors and its future
126 June 28 (Fri.), 13:30 PM  #1323, E6-2  Dr. Yusuke Kozuka  Magnetic domains and domain wall conduction in pyrochlore iridate thin films and heterostructures file
125 Oct. 27th(Thu) 4PM  #1323(E6-2)  Dr. 이 강 희, KAIST, Mechnical Engineering  Terahertz Metal Optics
124 Nov. 18th (Fri) 10:30 a.m.  #5318(5th fl.)  Dr. 최 순 원, Havard University  Non-equilibrium many-body spin dynamics in diamond
123 September 26 (Thu.), 16:00 PM  #1323, E6-2  Han Seb Moon  Entanglement Swapping with Autonomous Polarization-Entangled Photon-Pairs from Warm Atomic Ensemble file
122 August 27 (Tue.), 4:00PM  Rm. 1323, E6  Hiroshi Eisaki  Critical current properties of Fe-based superconductors file
121 August. 1st (Thu), 14:00  E6 Room(#1323)  Hyeok Yoon  Low-density Superconductivity in SrTiO3 Probed by Planar Tunneling Spectroscopy file
120 Jun. 16 (Thu) 4PM  #1323(E6-2, 1st fl.)  Hyochul Kim, Samsung Advanced Institute of Technology  Quantum information processing using quantum dots and photonic crystal cavities
119 June 27 (Thu), 2:00 PM  #2502, E6-2  Hyun-Yong Lee  Gapless Kitaev Spin Liquid to Loop and String Gases file