visual
visual

세미나

  • HOME
  • >
  • 소식
  • >
  • 세미나
장소 KI bldg. 5th fl. Room B501 & Zoom 
일시 Jan. 18(Tue), 2pm-3pm 
연사 YoungJu Jo (Stanford University) 

[Seminar]

18 Jan 2022, Tue, 2pm-3pm, KI bldg. 5th fl. Room B501

Zoom: https://kaist.zoom.us/j/89586032430

회의 ID: 895 860 324 30

 

Data-driven interrogation of biological dynamics:
from subcellular interactions to neuronal networks in vivo

 

 

YoungJu Jo

PhD Candidate in Applied Physics, Deisseroth Laboratory, Stanford University

 

 

Biological systems are nonlinear dynamical systems consisting of heterogeneous entities. Understanding the logic of the complex spatiotemporal dynamics in such systems, robustly implementing specific biological functions, may require new approaches beyond the traditional hypothesis-driven experimental designs. Here we present a data-driven approach, enabled by high-throughput experimental and computational technologies, across multiple scales. We first discuss a computational imaging technique for simultaneously visualizing multiple aspects of subcellular dynamics [1, 2], its potential combination with molecular optogenetics to study the cell signaling networks, and the remaining challenges in these systems. Then we turn to neuronal networks in behaving animals where high-dimensional neural population activity could be reliably measured and perturbed over extended time. Synergizing with recent technical advances, we propose and experimentally demonstrate a unified deep learning framework to identify the underlying neural dynamical systems, reverse-engineer the neural computation implemented by the dynamics, and design spatiotemporally patterned optogenetic stimulation for naturalistic manipulation of animal behavior [3]. Application of this framework to the mouse habenular circuitry reveals cell-type-specific reward history coding implemented by line attractor dynamics [4].

 

References:

1. Jo*, Park* et al. Science Advances 3(8), e1700606, 2017.

2. Jo*, Cho*, Park* et al. Nature Cell Biology 23, 1329–1337, 2021.

3. Jo et al. in preparation.

4. Sylwestrak*, Vesuna*, Jo* et al. in revision.

 

문의: 박용근 교수 (내선:2514)

 

 

번호 일시 장소 연사 제목
322 May. 14 (Fri.), 04:00 PM  Online seminar  Dr. Je-Hyung Kim(UNIST)  Spatial and temporal separation of environmental dephasing sources from solid-state quantum emitters file
321 May. 14 (Fri.), 02:30 PM  Online seminar  Dr. Suyong Jung(KRISS)  Electrically tunable spin valve effect in vertical van-der-Waals magnetic tunnel junctions file
320 Jun. 11 (Fri.), 02:30 PM  Online seminar  Dr. Jin Woong Cha(KRISS)  Engineering sound waves and vibrations in multi-mode nanomechanical systems file
319 Jun. 11 (Fri.), 04:00 PM  Online seminar  Dr. Keun Su Kim(Yonsei University)  Pseudogap in surface-doped black phosphorus file
318 7월 29일(목) 오후 2시 ~ 오후 4시  Online seminar  Dr. Kunio Kaneta(KIAS)  Gravitationally Induced Dark Sector and Inflationary Dynamics file
317 May 27,(Fri), 11:00 AM  Online seminar  Prof. Gray Rybka(University of Washington)  Current Status and Future Plans of ADMX file
316 3pm, 19th May  online  Jonghee Yoon, PhD (Assistant professor, Department of Physics, Ajou University)  (광학분야 특별세미나)Development of a multimodal optical system for improved disease diagnosis
315 Nov. 20 (Fri.), 04:00 PM  Online  Dr. Dohun Kim  Coherent control of field gradient induced quantum dot spin qubits
314 Nov. 20 (Fri.), 02:30 PM  Online  Dr. Doohee Cho  Lumpy Cooper pairs in an iron-based superconductor
313 Dec. 11 (Fri.), 02:30 PM  online  Myung Hwa Jung(Sogang Univ.)  Antisymmetric interlayer exchange coupling in magnetic multilayers
312 Dec. 11 (Fri.), 04:00 PM  online  Hyobin Yoo(Sogang Univ.)  Atomic and electronic reconstruction at van der Waals interface in twisted 2D materials
311 Dec.23(Wed), 10:00~16:00  Online  Prof. YongKeun Park (KAIST) and etc.  Online workshop for Quantitative Phase Imaging file
310 Feb.17(Wed)~19(Fri), 09:00~11:00AM  Online  Prof. Subir Sachdev (Harvard University)  석학 대중 강연 및 강의 시리즈 file
309 Mar 2 (Tue.), 16:00  Online  Dr. Dmitry Svintsov  Sensitive terahertz detection with graphene-based transistors file
308 4pm, 31th March  online  최현용 (서울대학교 물리천문학부)  (광학분야 특별세미나)Ultrafast time-resolved spectroscopy in topological materials
307 3pm, 19th May  online  Jonghee Yoon, PhD (Assistant professor, Department of Physics, Ajou University)  (광학분야 특별세미나)Development of a multimodal optical system for improved disease diagnosis
306 2016/09/05-12/12 4PM  Natual Scien Bldg.(E6)m #1501  Yeong Kwan Kim 외  Physics Colloquium : 2016 Fall file
305 May 19, 2016 (Thur.) 3PM  May 19, 2016 (Thur.) 3PM,  Dr. Michael Betz, CERN  The CERN Resonant WISP Search: Development, Results and Lesson-Learned
304 2017.1.9(Mon), 4PM  Lecture Hall, College of Natural Sciences [#1501,E6-2]  Prof. John Michael Kosterlitz, Brown University  Topological Defects and Phase Transitions" file
303 4월 18일(월), 15:30~  KI빌딩(E4), 강의실 B501 (5F)  Prof. Robert A. DiStasio Jr. (Cornell University)  First Principles Approaches for Intermolecular Interactions: From Gas-Phase Dimers to Liquid Water and Molecular Crystal Polymorphism file