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장소 E4(KI Building), Connect room (2nd fl.) 
일시 2015/12/09, 11AM 
연사 Arjun G. Yodh (University of Pennsylvania) 

Functional Imaging & Monitoring of Brain & Breast with Diffuse Light


ABSTRACT
Functional diffuse optical imaging and spectroscopy of tissue is gaining momentum as a diagnostic in a variety of medical scenarios including breast cancer imaging, functional activation and clinical studies of brain, cancer therapy monitoring and the investigation of muscle disease [1, 2, 3]. After a short introduction to diffuse optics, I will review several recent clinical studies from my lab, particularly those oriented towards breast cancer and brain function. Central to the breast cancer effort is a pilot clinical trial [4] which has taken important steps towards quantitative assessment of diffuse optics for detection and characterization of tumors [5], and helps to spin-off problems such as cancer therapy monitoring. A second important application of diffuse optical methods is in the area of brain function and physiology wherein the interplay between tissue oxygen consumption, vascular supply, and regulatory effects remains poorly understood. The utility of this approach in brain will be demonstrated in several contexts, including the care of acute ischemic stroke (AIS) patients in the clinic [6, 7].


REFERENCES
1. Durduran, T., Choe, R., Baker, W.B, and Yodh, A.G., Reports on Progress in
Physics, 73, 076701 (2010).
2. Mesquita, R.C., Durduran, T., Yu, G., Buckley, E.M., Kim, M.N., Zhou, C., Choe, R., Sunar, U., Yodh, A.G., Philosophical Transactions of the Royal Society A 369, 4358-4379 (2011).
3. Durduran, T., and Yodh, A.G., Neuroimage 85, 51-63 (2014).
4. Choe, R., Konecky, S.D., Corlu, A., Lee, K., Durduran, T., Busch, D.R., Pathak, S., Czerniecki, B.J., Tchou, J., Fraker, D.L., DeMichele, A., Chance, B., Arridge, S.R., Schweiger, M., Culver, J.P., Schnall, M.D., Putt, M.E., Rosen, M.A., and Yodh, A.G., Journal of Biomedical Optics 14, 024020 (2009).
5. Busch, D.R., Choe, R., Rosen, M.A., Guo, W., Durduran, T., Feldman, M.D., Mies, C., Czerniecki, B.J., Tchou, J., DeMichele, A., Schnall, M.D., and Yodh, A.G., Biomedical Optics Express 4, 105-121 (2013).
6. Durduran, T., Zhou, C., Edlow, B.L., Yu, G., Choe, R., Kim, M.N., Cucchiara, B.L., Putt, M.E., Shah, Q., Kasner, S.E., Greenberg, J.H., Yodh, A.G., and Detre, J.A., Optics Express 17, 3884-3902 (2009).
7. Kim, M.N., Edlow, B.L., Durduran, T., Frangos, S., Mesquita, R.C., Levine, J.M., Greenberg, J.H., Yodh, A.G., and Detre, J.A., Nerocritical Care 20, 443-453, DOI
10.1007/s12028-013-9849-7 (2014).

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248 Nov. 29(Tue) 4p.m.  #1323(E6-2. 1st fl.)  Dr. SungBin Lee, KAIST  Symmetry Protected Kondo Metals and Their Phase Transitions
247 Dec. 8(Thu) 4p.m.  #1323(E6-2. 1st fl.)  Dr. Jinhyoung Lee, Hanyang University  Dynamical Resonance between Two Optical Cavities via Optomechanical Oscillator
246 Dec. 9(Fri), 1:30 p.m.  #1323(E6-2. 1st fl.)  Dr. Jae Yoon Cho, POSTECH  Entanglement area law in strongly-correlated systems
245 Feb. 1 (Wed.), 2p.m.  #1323(E6-2. 1st fl.)  Dr. Michihisa Yamamoto, Department of Applied Physics, The University of Tokyo  Quantum electron optics using flying electrons
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242 October 11 (Thu.), 16:00 PM  #1323, E6-2  Prof. Joung-Real Ahn  Dirac electrons in a graphene quasicrystal file
241 October 15 (Mon.), 16:00 PM  #1323, E6-2  Dr. Yongjoo Baek  Universal properties of macroscopic current-carrying systems file
240 October 16 (Tue.), 10:00 AM  #1323, E6-2  Dr. Won-Ki Cho  Capturing protein cluster dynamics and gene expression output in live cells file
239 October 18 (Thu.), 10:00 AM  #1323, E6-2  Dr. Duyoung Min  Understanding membrane protein folding using single-molecule force techniques file
238 October 19 (Fri.), 10:00 AM  #1323, E6-2  Dr. Jongsoo Yoo  Energy conversion processes during magnetic reconnection in a laboratory plasma file
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235 June 27 (Wed.), 13:30 PM  #1323, E6-2  Dr. Jung Sik Park  Magnetic reversal of artificial spin ice file
234 May 9 (Wed.), 04:00 PM  #1323, E6-2  Prof. Jong-Soo Rhyee  Recent advances in thermoelectric bulk composites file
233 May 29 (Tue.), 04:00 PM  #1323, E6-2  Prof. Jae-Won Jang  Investigation on metal nanostructure/semiconductor junction and its applications file
232 May 311 (Thu.), 04:00 PM  #1323, E6-2  Prof. Teun-Teun Kim  Dynamic control of optical properties with gated-graphene metamaterials file
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