visual
visual

세미나

  • HOME
  • >
  • 소식
  • >
  • 세미나
날짜 2023-05-22 13:00 
일시 May 22th(Mon), 1:00pm 
장소 E6-6 119 
연사 Dr. John Bosco Balaguru Rayappan (SASTRA Deemed University) 
물리학과 이원희 교수 연구실에서 SASTRA Deemed University의 Professor. Rayappan을 초청하여 세미나를 개최합니다.
구성원 여러분들의 많은 관심과 참여 부탁 드립니다.
 
* Title: Design & Development of Electrochemical Biosensors for the Detection of T2DM Biomarkers 

* Speaker: Dr. John Bosco Balaguru Rayappan

* Date: 1:00 pm, 22th may 2023 (Monday)

* Place: E6-6 119 (no zoom broadcasting)


Abstract:
The screening of diabetes complications may greatly benefit from the adoption of point-of-care devices for detecting diabetes biomarkers in human blood plasma and urine samples. Preeminent Methylglyoxal (MG) and Carboxymethyl-lysine (CML) levels lead to various diseases and diabetes complications. Therefore, MG and CML are considered to be the potential biomarkers of diabetes mellitus, which are produced in the Maillard reaction and involved in the formation of advanced glycation end-products. In this background, we have developed electrochemical biosensors for the detection of MG and CML in human blood plasma and urine samples. An enzyme-based electrochemical MG biosensor was developed with a linear range of 1.0 - 7.5 μM concentration, sensitivity of 1.02 mA μM-1, limit of detection of 0.21 μM, limit of quantification of 0.70 μM and response time less than 10 s. The developed sensor was validated with 350 clinical samples and it exhibited a 90% of correlation with ELISA data. In addition, an enzyme-free antibody-based electrochemical sensor for the detection of CML was developed and it exhibited a linear range of 10 ng mL-1 – 500 μg mL-1. To obtain more accuracy in detecting the complications of diabetes, one can adopt a simultaneous detection of both MG and CML analytes with the multi-probe channel system.
 
번호 날짜 장소 제목
571 2024-12-17 15:00  E6, 1501호  Learning state preparation circuit for quantum phases of matter (Isaac H. Kim, UC Davis)
570 2024-11-21 16:00  자연동(E6) 1323호  Time-resolved photoemission: From bandstructure to orbital movies / Nanophotonics 초세대 협업 연구실 file
569 2024-11-21 11:00  E6-2 3441  3d Gravity and Tensor Model file
568 2024-11-18 10:30  응용공학동(W1-1) 1317호  Manipulation of antiferromagnetic magnon polarization in synthetic antiferromagnets
567 2024-11-13 12:00  Online  [11/13(수) 물리학과 세미나 안내] Separability as a window to mixed-state quantum phases and phase transitions / Tarun Grover (UC San Diego, Associate Professor)
566 2024-10-31 13:00  E6-2 / Rm. 3441  Mini-workshop on first-principles DFT methods and applications
565 2024-10-30 14:30  E6-2, #3441  [Seminar Invitation] Mario Cuoco (CNR-SPIN, c/o University of Salerno, Fisciano, Italy) / 2024.10.30. 14:30 / E6-2, #3441
564 2024-10-21 13:00  E6-2 #3441  [Physics Seminar] “Non-Hermitian Point-Gap Topology in Junction Systems” file
563 2024-10-17 16:00  온라인 (https://kaist.zoom.us/j/89289652931?pwd=eNz6xnTFrEMGXYj9fXpdBJsW9fEpJX.1)  Photonic Methods for Quantum Levitodynamics Beyond the Rayleigh Regime
562 2024-10-14 11:00  KI Building(E4), Matrix Hall(2nd Floor)  [RSVP, Oct 14th Mon] Ambassador of Hungary to Republic of Korea Special Lecture file
561 2024-10-02 12:00  E6-2, #3441  Data-driven discovery of neural computations through brain-wide and cell-type-specific dynamical systems file
560 2024-09-26 14:00  KAIST, Physics Bldg. (E6-2) / (Rm. 3441)  Quantum spin nematic phase in a square-lattice iridate
559 2024-09-03 12:00  자연과학동(E6-2) 1323  2024 가을학기 물리학과 특별세미나 전체 일정 (응집물리 및 광학분야) file
558 2024-09-02 16:00  자연과학동 1501호(공동강의실)  2024학년도 가을학기 물리학과 콜로키움(Physics Colloquium) file
557 2024-08-22 16:00  RM #C303, Creation Hall (3F), KAIST Munji Campus  [CAPP seminar] Development of a 12-20 GHz CO Intensity Mapping Receiver for Capturing the Star-formation History in the Early Universe file
556 2024-08-16 11:00  E6 1322 (no zoom broadcasting)  Cathodoluminescence for nanophotonics: Applications to plasmonic bandgap materials and perovskite semiconductors file
555 2024-08-14 11:00  E6, #3441  Pair Density Waves and Supercurrent Diode Effect in Altermagnets
554 2024-07-25 16:00  Rm. 3441, E6-2 (Advanced Physics Lecture Hall)  Generation and Certification of Optical Quantum States for Information Processing file
553 2024-07-23 16:00  KI Building(E4) Matrix Hall(2F)  Spin Conversion Research Towards Novel Spintronic Functionalities file
552 2024-07-22 14:00  E6-2 #3441  Nonthermal electronic orders in photo-doped Mott insulators