visual
visual

세미나

  • HOME
  • >
  • 소식
  • >
  • 세미나
날짜 2023-05-22 13:00 
연사  
장소 E6-6 119 
물리학과 이원희 교수 연구실에서 SASTRA Deemed University의 Professor. Rayappan을 초청하여 세미나를 개최합니다.
구성원 여러분들의 많은 관심과 참여 부탁 드립니다.
 
* Title: Design & Development of Electrochemical Biosensors for the Detection of T2DM Biomarkers 

* Speaker: Dr. John Bosco Balaguru Rayappan

* Date: 1:00 pm, 22th may 2023 (Monday)

* Place: E6-6 119 (no zoom broadcasting)


Abstract:
The screening of diabetes complications may greatly benefit from the adoption of point-of-care devices for detecting diabetes biomarkers in human blood plasma and urine samples. Preeminent Methylglyoxal (MG) and Carboxymethyl-lysine (CML) levels lead to various diseases and diabetes complications. Therefore, MG and CML are considered to be the potential biomarkers of diabetes mellitus, which are produced in the Maillard reaction and involved in the formation of advanced glycation end-products. In this background, we have developed electrochemical biosensors for the detection of MG and CML in human blood plasma and urine samples. An enzyme-based electrochemical MG biosensor was developed with a linear range of 1.0 - 7.5 μM concentration, sensitivity of 1.02 mA μM-1, limit of detection of 0.21 μM, limit of quantification of 0.70 μM and response time less than 10 s. The developed sensor was validated with 350 clinical samples and it exhibited a 90% of correlation with ELISA data. In addition, an enzyme-free antibody-based electrochemical sensor for the detection of CML was developed and it exhibited a linear range of 10 ng mL-1 – 500 μg mL-1. To obtain more accuracy in detecting the complications of diabetes, one can adopt a simultaneous detection of both MG and CML analytes with the multi-probe channel system.
 
번호 날짜 연사 제목
공지 2025-02-24 16:00    2025년 봄학기 콜로키움 안내
공지 2025-02-27 16:00    2025년 봄 물리학과 특별세미나 (광학/응집물리 분야)
214 2022-09-21 16:00    Materials and Device Nanofabrication of Optical Metasurfaces file
213 2022-09-22 11:00    2022 가을학기 응집물리 및 광학 세미나 전체 일정 file
212 2022-09-22 16:00    (광학분야 세미나) Quasi-particle-like optical vortices in magnetic materials
211 2022-09-23 11:00    [Update 세미나 영상] (응집물리 세미나) Steady Floquet-Andreev states in graphene Josephson junctions file
210 2022-09-29 16:00    (광학분야 세미나) Ultrafast THz Field-Induced Nonlinear Optics
209 2022-09-30 14:30    Putting a spin on the Josephson effect file
208 2022-09-30 16:00    Spin-orbit torque-based spintronic devices file
207 2022-10-04 16:00    Distinguishing 6d (1, 0) SCFTs
206 2022-10-06 13:00    Counting States with Global Symmetry
205 2022-10-07 11:00    [Update 세미나 영상] (응집물리 세미나) Competing orders in a vanadium-based kagome metal monolayer file
204 2022-10-13 16:00    (광학분야 세미나) Ultrafast Optics for Ultra-Precision Metrology and Realization of Flexible/Stretchable Laser-Induced-Graphene Electronics
203 2022-10-24 16:00    Physics Colloquim(Fall 2022) file
202 2022-10-26 10:00    Replica Higher-Order Topology of Hofstadter Butterflies in Twisted Bilayer Graphene
201 2022-10-27 16:00    (광학분야 세미나) Cavity optomechanical systems for quantum transduction
200 2022-10-28 11:00    [Update 세미나영상] (응집물리 세미나) Machine-Learning-Guided Prediction models and Materials discovery for high Tc cuprates file
199 2022-11-03 13:00    [High-Energy Theory Seminar] Supersymmetric observables via Fermi-gas method
198 2022-11-03 16:00    (광학분야 세미나) Single-photon emission from low-dimensional materials
197 2022-11-04 16:30    초세대 협업연구실 Quantum- & Nano-Photonics_Multifunctional neural probes with integrated nanophotonics file
196 2022-11-09 16:00    Radio Astronomy, Radio Interferometry, and Multi-wavelength Studies on Relativistic Jets
195 2022-11-10 16:00    Probing the Origin of Cosmic Infrared Background and Future Prospects with SPHEREx