visual
visual

세미나

  • HOME
  • >
  • 소식
  • >
  • 세미나
날짜 2023-05-22 13:00 
일시 May 22th(Mon), 1:00pm 
장소 E6-6 119 
연사 Dr. John Bosco Balaguru Rayappan (SASTRA Deemed University) 
물리학과 이원희 교수 연구실에서 SASTRA Deemed University의 Professor. Rayappan을 초청하여 세미나를 개최합니다.
구성원 여러분들의 많은 관심과 참여 부탁 드립니다.
 
* Title: Design & Development of Electrochemical Biosensors for the Detection of T2DM Biomarkers 

* Speaker: Dr. John Bosco Balaguru Rayappan

* Date: 1:00 pm, 22th may 2023 (Monday)

* Place: E6-6 119 (no zoom broadcasting)


Abstract:
The screening of diabetes complications may greatly benefit from the adoption of point-of-care devices for detecting diabetes biomarkers in human blood plasma and urine samples. Preeminent Methylglyoxal (MG) and Carboxymethyl-lysine (CML) levels lead to various diseases and diabetes complications. Therefore, MG and CML are considered to be the potential biomarkers of diabetes mellitus, which are produced in the Maillard reaction and involved in the formation of advanced glycation end-products. In this background, we have developed electrochemical biosensors for the detection of MG and CML in human blood plasma and urine samples. An enzyme-based electrochemical MG biosensor was developed with a linear range of 1.0 - 7.5 μM concentration, sensitivity of 1.02 mA μM-1, limit of detection of 0.21 μM, limit of quantification of 0.70 μM and response time less than 10 s. The developed sensor was validated with 350 clinical samples and it exhibited a 90% of correlation with ELISA data. In addition, an enzyme-free antibody-based electrochemical sensor for the detection of CML was developed and it exhibited a linear range of 10 ng mL-1 – 500 μg mL-1. To obtain more accuracy in detecting the complications of diabetes, one can adopt a simultaneous detection of both MG and CML analytes with the multi-probe channel system.
 
번호 날짜 장소 제목
109 2023-05-15 16:00  CAPP Seminar Room C303, Creation Hall, KAIST Munji Campus  Role of dark Higgs boson in DM physics and cosmology file
108 2023-05-17 14:00  E6 #1323  Optical Response in the multilayer thin films
107 2023-05-17 16:30  Zoom  Detecting Hidden Photon Dark Matter via the Excitation of Qubits file
106 2023-05-18 16:00  E6-2 #1323  (광학분야 세미나)Dielectric metasurfaces for optimized optical system and spatial light modulators
105 2023-05-19 11:00  E6-2 #1323  (응집물리 세미나)Dipole condensations in Tilted Bose-Hubbard Chains
» 2023-05-22 13:00  E6-6 119  Design & Development of Electrochemical Biosensors for the Detection of T2DM Biomarkers
103 2023-05-26 11:00  E6-2 #1323  (응집물리 세미나)Spectral Analyses of Stochastic Charge Trapping in Oxide Heterostructures file
102 2023-05-31 16:00  E6-2, #2502  [High-Energy Theory Seminar] Resurgence and complex Chern-Simons theory
101 2023-06-01 16:00  E6-2, #5301  Hall viscosity and topological phenomena
100 2023-06-01 16:00  E6-2 #1323  (광학분야 세미나)Quantum sensing using a squeezed light from hot Rb vapor
99 2023-06-08 16:00  E6-2, #1323  Thermal decoupling in high-Tc cuprate superconductors
98 2023-06-14 16:00  CAPP Seminar Room C303, Creation Hall, KAIST Munji Campus  [CAPP seminar] EMC at CERN file
97 2023-06-14 16:00  E6-2, #2502  [High-Energy Theory Seminar]Vertex algebras and extended operators in 4d N=2 SCFTs
96 2023-06-15 16:00  CAPP Seminar Room C303, Creation Hall, KAIST Munji Campus  [CAPP Seminar] Cryogenic electronics for ion traps file
95 2023-06-16 13:00  E6-2, #2502  Quantum critical states under extreme conditions
94 2023-06-22 16:00  CAPP Seminar Room C303, Creation Hall, KAIST Munji Campus  [CAPP Seminar] The muon g-2 puzzle file
93 2023-06-22 16:00  E6-2,1323  [High Energy Physics Seminar] The Branes Behind Generalized Symmetry Operators
92 2023-06-23 11:00  E6-6, #119  Visualizing orbital quantum phenomena at room temperature
91 2023-06-26 11:00  E6, Rm#1323  Quantum computing on magnetic racetracks with flying domain wall qubits
90 2023-06-30 11:00  E6-6 #1501  The Dual Mode Quantum Computer file